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Ehlers-Danlos Syndrome: Understanding Connective Tissue, the Nervous System, and Chiropractic Support

  • Writer: Dr. Alec
    Dr. Alec
  • Oct 9, 2025
  • 3 min read

Ehlers-Danlos Syndrome (EDS) is a connective tissue disorder that affects collagen, joint stability, and nervous system function. For patients in Indianapolis living with EDS, everyday movement can feel unpredictable, and injuries may occur more easily. At Electric Life Chiropractic, we focus on supporting joint stability, nervous system regulation, and functional movement, helping patients move safely, reduce pain, and improve quality of life.




What Ehlers-Danlos Syndrome Is

  • Definition: A genetic condition affecting collagen production, leading to hypermobile joints, fragile tissues, and increased injury risk.

  • Types:

    • Hypermobile EDS (hEDS): Most common; joint hypermobility, chronic pain

    • Classical EDS: Skin hyperextensibility and fragility

    • Vascular EDS: Fragile blood vessels, serious complications

  • Symptoms:

    • Joint hypermobility or frequent subluxations

    • Chronic musculoskeletal pain

    • Fatigue and delayed recovery

    • Digestive or autonomic symptoms in some patients

Key Structures Involved:

  • Collagen-rich connective tissue throughout the body

  • Joints: shoulders, knees, hips, spine

  • Ligaments and tendons

  • Stabilizing muscles: core, scapular, hip, and postural muscles

  • Nervous system: proprioception, balance, and autonomic regulation


Neurological Implications

  • Proprioceptive Dysfunction: Hypermobile joints can confuse the brain’s sense of joint position

  • Nervous System Overload: Chronic pain and instability increase sympathetic nervous system activity

  • Balance & Coordination Challenges: Reduced joint stability affects motor control and functional movement

  • Neuroplasticity Potential: Targeted rehab can retrain movement patterns and improve joint awareness


How It Happens – Causes

  • Genetic mutations affecting collagen

  • Hypermobile joints and ligament laxity lead to recurrent joint strain

  • Weak stabilizer muscles or neuromuscular control deficits increase injury risk

  • Secondary factors: repetitive stress, trauma, sedentary lifestyle, poor posture


Physical & Musculoskeletal Considerations

  • Joint hypermobility can cause frequent subluxations or dislocations

  • Muscular fatigue: stabilizer muscles work harder to compensate for loose joints

  • Chronic postural strain: rounded shoulders, lumbar lordosis, or spinal misalignment

  • Risk of overuse injuries: tendinitis, bursitis, or ligament injuries


Hormonal & Systemic Considerations

  • Chronic pain and instability can increase cortisol levels, contributing to fatigue and stress sensitivity

  • Autonomic dysregulation may lead to digestive issues, dysautonomia, or heart rate irregularities

  • Sleep disturbances common due to pain, sympathetic dominance, or anxiety

  • Exercise and chiropractic care support parasympathetic activation and recovery


Practical Daily Living Tips

Joint Protection & Safe Movement

  • Avoid hyperextension or end-range joint positions

  • Use supportive devices: braces, kinesiology tape, or ergonomic seating

  • Pace activities to prevent fatigue and overuse

Movement & Stabilization

  • Core activation and hip/glute stabilizers strengthen pelvic and spinal support

  • Scapular and shoulder stabilizers protect upper body joints

  • Low-impact resistance exercises to improve neuromuscular control

Lifestyle & Recovery

  • Sleep hygiene: maintain consistent schedule, reduce stimulants

  • Nutrition: adequate protein, Omega-3s, and micronutrients for connective tissue health

  • Hydration and gentle activity for joint lubrication

Cognitive & Emotional Support

  • Mindfulness and breathing exercises reduce sympathetic dominance

  • Support groups for EDS can help with coping strategies

  • Gentle stress management supports nervous system regulation


Rehabilitation & Functional Support

Safe Mobility Exercises

  • Gentle joint mobilizations within safe range

  • Dynamic warm-ups to activate stabilizers

  • Stretching only to relieve tightness—not force hyperextension

Strengthening & Stability

  • Core stabilization (Bird Dog, Dead Bug, modified planks)

  • Hip and glute strengthening

  • Scapular and shoulder stabilizers

  • Low-impact resistance exercises for controlled neuromuscular activation

Neuroplasticity & Proprioceptive Training

  • Mindful joint awareness exercises

  • Balance and coordination drills on stable surfaces

  • Gradual integration into daily functional activities

At-Home Support

  • Ice or heat for flare-ups

  • Kinesiology tape for high-risk joints

  • Ergonomic adjustments for work or daily routines

  • Education on safe movement and joint protection


Long-Term Functional Perspective

  • Structural hypermobility may not fully “normalize,” but functional improvements are achievable

  • Patients can reduce pain, prevent injuries, and improve daily function

  • Consistent care improves proprioception, joint control, and nervous system regulation, supporting lifelong mobility and quality of life


Recovery & Results

  • Improvement in joint stability and functional movement: 4–12 weeks

  • Chronic pain management: ongoing, with functional strengthening and nervous system regulation

  • Early intervention reduces injury risk, hypermobility complications, and functional limitations


Key Takeaways

  • EDS affects connective tissue, joints, and the nervous system, leading to hypermobility and chronic pain

  • Chiropractic care, FMSA-guided rehab, and functional strengthening improve stability, proprioception, and nervous system coordination

  • Daily strategies, posture awareness, and movement modification help patients move safely and confidently

  • Functional improvements can enhance quality of life and independence, even with lifelong hypermobility


If you or a loved one are living with Ehlers-Danlos Syndrome or joint hypermobility, chiropractic care can help support safer movement, joint stability, and nervous system regulation. At Electric Life Chiropractic in Indianapolis, we use Functional Movement Screening Analysis (FMSA) to create personalized plans that strengthen stabilizers, optimize alignment, and improve daily function. Schedule a consultation today to move more safely and comfortably.


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